Proteolytic control of Interleukin-11 and Interleukin-6 biology
نویسندگان
چکیده
منابع مشابه
Signal transduction of interleukin-11 and interleukin-6 α-receptors
The cytokines Interleukin (IL)-11 and IL-6 are important mediators that regulate differentiation and proliferation of immune cells. Both cytokines bind to unique non-signaling α-receptors (IL-11R and IL-6R, respectively), and the resulting cytokine/cytokine receptor complexes recruit a homodimer of the signal-transducing β-receptor glycoprotein (gp)130. Gp130 is expressed ubiquitously, whereas ...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
سال: 2017
ISSN: 0167-4889
DOI: 10.1016/j.bbamcr.2017.06.008